SS-31

SS-31 (Elamipretide) — Tetrapeptide with Mitochondrial Tropism

SS-31, also known as Elamipretide, is a synthetic tetrapeptide of the Szeto-Schiller family. Its alternating aromatic-cationic structure enables selective accumulation in the inner mitochondrial membrane, where it interacts with cardiolipin — a property that has made it a reference tool in preclinical research on mitochondrial bioenergetics, lipid peroxidation and respiratory-chain function.

What it is studied for

In the published preclinical literature, SS-31 (Elamipretide) has been investigated in laboratory and in-vitro models for its effects on:

• Mitochondrial function — stabilisation of cardiolipin and the inner mitochondrial membrane
• Cellular energy (ATP) — restored bioenergetics in mitochondrial-dysfunction models
• Antioxidant activity — reduced reactive-oxygen-species and oxidative stress
• Organ & age-related models — cardiac, renal, neural and skeletal-muscle decline

In plain terms: a leading research tool for mitochondrial health and cellular energy.

Molecular Profile

• Sequence: D-Arg-Dmt-Lys-Phe-NH₂
• Molecular weight: ~640 Da
• Purity: ≥98% (HPLC)
• Format: Sterile lyophilizate in a 10 mg vial

Storage Conditions

• Store at -20 °C, protected from light
• After reconstitution: store at 2–8 °C and use within 28 days

Legal Disclaimer: Reagent intended exclusively for in vitro scientific research by qualified professionals. Not intended for human or veterinary consumption, nor for any therapeutic, diagnostic, or cosmetic purpose. This product is not a medicine, food supplement, or cosmetic. Nexus Peptides accepts no responsibility for any use outside the scope of laboratory research.